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Updates from MUSC's Offices of Research Administration


ORI
ORI
ORI's Blog

DO YOU WORK WITH HUMAN PLURIPOTENT STEM CELLS?

Then you should know that MUSC has adopted a new campus policy for the review and approval of human pluripotent stem cell research. The “MUSC Research Using Human Stem Cells Policy” will take effect on July 1, 2017. In order to be compliant, MUSC leadership has charged a new oversight body, the Stem Cell Research Oversight (SCRO) committee, with oversight responsibilities for all research projects that fall under this policy.

Applicability and Scope of Oversight of the SCRO Policy

The scope of the MUSC Research Using Human Stem Cells Policy is limited to a well-defined subset of life sciences research that involves the storage of human embryonic stem cells and the derivation or use of all types of human pluripotent stem cells at MUSC.  The aim of this policy is to help ensure that such research is conducted with the highest ethical and scientific research standards, and in compliance with all applicable federal and state regulations, MUSC policies, and the requirements of extramural research sponsors.  Non-compliance with this Policy may result in suspension, limitation, or termination of Federal research funding.

Principal Investigator Responsibilities

It is the responsibility of the Principal Investigator to identify research involving the derivation or use of human pluripotent stem cells and notify the SCRO for review.  

SCRO Notification of Research with Human Stem Cells

The formal SCRO review starts with the PI submission of a SCRO registration form. Instructions for submitting this form are available on the SCRO website. The SCRO will review the application and determine whether or not the project indeed falls into the scope of human stem cell research oversight. All individuals involved in this scope of research will be required to complete the SCRO training module in the online CITI Human Stem Cell program.   

Researchers with questions are encouraged to talk to the SCRO Program Manager (Dr. Yashmin Karten, 843-792-6521, karteny@musc.edu).

 

Resources:

MUSC website on SCRO

http://research.musc.edu/ori/SCRO  

MUSC Research Using Human Stem Cells Policy

http://research.musc.edu/ori/SCRO/Policies%20and%20Procedures.html

National Academies of Sciences Guidelines  

https://doi.org/10.17226/11278

NIH Guidelines on Human Stem Cell Research

https://stemcells.nih.gov/policy/2009-guidelines.htm 

NIH Human Embryonic Stem Cell Registry

http://stemcells.nih.gov/research/registry/ 

International Society for Stem Cell Research

http://www.isscr.org/